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Table of Contents
What Is Osteoporosis?
Osteoporosis is an alarming condition that weakens bones, making them thinner and less dense.
Normally, bones are dense and sturdy, supporting weight and absorbing impacts. However, with age, bones naturally lose density and regrowth capacity. In osteoporosis, bones become notably fragile and weaker.
Osteoporosis is unnoticeable until a bone breaks. It can affect any bone but commonly impacts the hips, wrists, and spine.
Is It Common?
Over 50 million people around the world have it. It’s particularly common in individuals over 50, with estimates indicating that half of assigned females at birth and 1 in 4 assigned males at birth in this age group have osteoporosis.
One in three adults over 50 who don’t have osteoporosis already exhibit reduced bone density, known as osteopenia. Osteopenia is an early indication of osteoporosis and, if left untreated, can progress to full-blown osteoporosis.
What Are the Symptoms of Osteoporosis?
Unlike many other health issues, osteoporosis is often called a silent disease because it doesn’t show typical symptoms. While osteoporosis itself doesn’t cause obvious symptoms, you might notice changes in your body indicating bone loss, such as:
- Losing an inch or more of height.
- Changes in posture, like stooping or bending forward more.
- Shortness of breath due to compressed spinal discs.
- Lower back pain.
Can Cannabinoids Work as Alternative Treatment to Osteoporosis?
Marijuana shows promise as an alternative treatment for osteoporosis by interacting with cannabinoid receptors in the body, affecting bone metabolism and potentially improving bone density and strength.
These cannabinoids affect bone health through interactions with cannabinoid receptors in the human body, primarily CB1 and CB2 receptors.
- CB1 receptors: Seen in the central nervous system, CB1 receptors regulate bone resorption and formation.
- CB2 receptors: Primarily located in peripheral tissues, including bone cells, CB2 receptors modulate bone metabolism and inflammation.
CB1 receptors regulate bone formation through skeletal nerve terminals, while CB2 receptors are found in bone cells and promote bone formation while reducing bone breakdown.
Reminder: While further research is needed to fully understand the effects of cannabinoids on osteoporosis and ensure their safety and effectiveness, early findings are encouraging. Cannabinoids could offer a new approach to managing osteoporosis, especially for those who don’t respond well to traditional treatments or experience side effects.
Cannabinoids vs Traditional Osteoporosis Treatments
| Feature | Cannabinoids | Traditional Osteoporosis Treatments |
| Mechanism of Action | Interacts with cannabinoid receptors, potentially impacting bone metabolism and density. | Act on bone cells to either slow down bone loss or help build new bone. |
| Types of Treatment | Derived from cannabis plants may include THC, CBD, or other cannabinoids. | Various medications such as bisphosphonates, hormone therapy, selective estrogen receptor modulators (SERMs), calcitonin, and monoclonal antibody therapy. |
| Administration | Can be consumed orally, through inhalation, or topical application. | Typically administered orally, through injections, or as intravenous infusions. |
| Potential Side Effects | Risk effects may include dizziness, dry mouth, fatigue, and changes in appetite. | They differ depending on the medication and may include gastrointestinal upset, headache, muscle pain, and rare but serious side effects like jaw osteonecrosis. |
| Effectiveness | Preliminary research suggests potential benefits for bone health, but further studies are needed to confirm efficacy and safety. | Traditional treatments have been extensively studied and shown to minimize fracture risk. |
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| Feature | Snow Leopard | Cali Gold | Kush Cake |
| Flavours | Spicy, Woody | Skunky, Lemon | Vanilla, Lemon |
| Strain Types | Indica | Hybrid (Sativa Dominant) | Hybrid (Indica Dominant) |
| THC | 24 | 24 | 24 |
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Frequently Asked Questions
How Is Osteoporosis Diagnosed?
Healthcare providers diagnose osteoporosis through a bone density test, DEXA, or scan. This imaging test measures bone strength using X-rays to assess bone calcium and mineral levels.
Low X-rays evaluate bone density and mineral content during a bone density test, similar to a standard X-ray. It’s an outpatient procedure, meaning you can go home afterward without the need for hospitalization or needles.
Regular bone density tests are recommended for individuals with a family history of osteoporosis, those over 50, or those with osteopenia, as monitoring bone density changes is significant for early detection and prevention of fractures.
How Is Osteoporosis Treated?
Your healthcare provider will assess a combination of treatments to slow bone loss and strengthen existing bone tissue, focusing on preventing fractures.
Common treatments for osteoporosis include:
- Exercise: Regular weight-bearing exercises like walking, yoga, Pilates, and tai chi can strengthen bones, muscles, tendons, and ligaments while improving balance. Your provider may suggest exercises tailored to your needs and involve working with a physical therapist.
- Vitamin and mineral supplements: Depending on your needs and dosage requirements, your provider may prescribe calcium or vitamin D supplements.
- Medications: Depending on your condition, your provider may prescribe hormone therapies such as estrogen or testosterone replacement, bisphosphonates, or other medications like parathyroid hormone (PTH) analogs, denosumab, or romosozumab for severe osteoporosis or high fracture risk. These medications are often administered through injections.
How Can I Lower My Risk of Osteoporosis?
Usually, exercise and ensuring adequate calcium and vitamin D intake in your diet are sufficient for prevention. The health specialist will assist you in deciding the best combination of treatments for your bone health.
Follow these safety tips to minimize injury risk:
- Always wear your seatbelt.
- Use appropriate protective gear for activities and sports.
- Keep your home and workplace clutter-free to avoid tripping hazards.
- Use proper tools or equipment to reach items at home; avoid standing on chairs, tables, or countertops.
- Maintain a healthy diet and exercise routine.
- If you have difficulty walking or are at increased risk of falls, consider using a cane or walker.
Main reference:
Other sources:
- https://www.medicalnewstoday.com/articles/297012
- https://my.clevelandclinic.org/health/diseases/4443-osteoporosis
- https://www.news-medical.net/health/Cannabinoid-Receptors.aspx
- https://emedicine.medscape.com/article/330598-treatment?form=fpf
Author Information:
- Mechoulam R. Discovery of endocannabinoids and some random thoughts on their possible roles in neuroprotection and aggression. Prostaglandins Leukot Essent Fatty Acids. 2002; 66: 93–9
- Qaseem A, Forciea MA, McLean RM, Denberg TD; Clinical Guidelines Committee of the American College of Physicians; Barry MJ, Cooke M, Fitterman N, Harris RP, Humphrey LL, Kansagara D, McLean RM, Mir TP, Schünemann HJ. Treatment of Low Bone Density or Osteoporosis to Prevent Fractures in Men and Women: A Clinical Practice Guideline Update From the American College of Physicians. Ann Intern Med. 2017 Jun 6;166(11):818-839. doi: 10.7326/M15-1361. Epub 2017 May 9. Erratum in: Ann Intern Med. 2017 Sep 19;167(6):448. PMID: 28492856.
